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Allergies are one of the top reasons that people in the United States visit a doctor. Up to 50 million Americans have some type of allergy. An allergy is an adverse reaction by your body’s immune system to a substance that does not bother other people who are not allergic to it. Any substance that triggers an allergic reaction is called an allergen. Some common allergens are pollen, dust mites, mold spores, pet dander, latex, various foods, insect stings and certain medicines.